Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay
نویسندگان
چکیده
منابع مشابه
Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.
OBJECTIVE To evaluate an enzyme-linked immunospot assay (ELISPOT) for the diagnosis of tuberculosis (TB) in HIV-infected children with suspected TB and to compare the performance of ELISPOT with the tuberculin skin test (TST). METHODS Interferon-gamma responses to Mycobacterium tuberculosis-specific antigens were measured by ELISPOT in HIV-infected children with suspected TB. HIV-infected and...
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Gamma interferon (IFN-gamma) release assays have been proven to be useful in the diagnosis of Mycobacterium tuberculosis infection. Nevertheless, their specificity and sensitivity vary among the different populations studied. Here, we evaluate the value of an in-house IFN-gamma enzyme-linked immunospot (ELISPOT) assay in the diagnosis of active tuberculosis (TB) in Shenzhen, China, where the pr...
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ژورنال
عنوان ژورنال: AIDS
سال: 2009
ISSN: 0269-9370
DOI: 10.1097/qad.0b013e32832956ad